A typical pharmacy has shelf after shelf of medicines that can be sold without a doctor's prescription. These are called over-the-counter (OTC) drugs. Many concerned mothers wonder about the safety of these medications while they are breastfeeding a baby. While there are many brands and varieties of drugs on the market, there is a relatively small list of active ingredients in all those products. Careful review of the product label is an essential part of responsible and safe use of these medicines. Some preparations have more than one active ingredient.