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Phenylketonuria (PKU) is an inherited metabolic disorder in which an affected person is less able to process the amino acid phenylalanine. Abnormally high levels of phenylalanine in the blood and tissues can cause a variety of toxic effects, including brain damage. All infants born in hospitals in the United States, and much of the rest of the first world, are routinely tested for PKU.
Many women choose to consume alcohol during their reproductive years. For most people, alcohol consumption in moderation is not harmful but for a fetus, alcohol exposure can be devastating. The office of the US Surgeon General recommends complete abstinence from alcohol for women who are planning to become pregnant and throughout all stages of their pregnancy.1
With respect to milk supply in women taking methylergonovine, we have found that a single post-partum dose will suppress prolactin levels, but doesn't seem to have much of a noticeable effect on supply. Existing studies are conflicted regarding this drug's effect on milk supply if used for more than a single post-partum dose.
G6PD deficiency is a metabolic disorder in which an enzyme in red blood cells, Glucose-6-Phosphate Dehydrogenase, does not work as well as it should. This deficiency makes the blood begins to break down during periods of significant oxidative stress, such as after ingestion of certain drugs and foods.
Neonatal hypoglycemia (low blood sugar in a new baby) is a common problem in hospital nurseries. Some infants can have low blood sugar and show no symptoms, others become jittery and may feed poorly, and in severe cases, the infant may suffer brain damage or have developmental delay.
The last few years have seen a resurgence of vaccine-preventable diseases in the United States. Whatever the cause of this may be, increasing incidence of these diseases poses a particular risk to patients who are not able to receive the vaccines, including babies less than 3 months of age.
A recent study explored the relationship between maternal colonization (bacteria on the mother’s skin surface) with Methicillin Sensitive Staphylococcus Aureus (MSSA), during pregnancy and delivery to determine the association with...
Breast cancer is the most common cancer in women. In 1990, the incidence of breast cancer was 5–7 per 100 women in developed countries in patients less than 70 years of age, and 1–2 per 100 in Asian and African countries.1
Several studies have suggested that breastfeeding may reduce the risk of several types of breast cancers.
Asthma is a common chronic inflammatory disease of the airways characterized by recurring symptoms of reversible airflow obstruction and bronchospasm. Symptoms include wheezing, coughing, chest tightness and shortness of breath.
Schizophrenia is a psychotic disorder, which causes severely impaired thinking, emotions, and unusual behaviors. Schizophrenic patients are typically unable to recognize sensory stimuli and may have enhanced perceptions of sounds, colors, and other features of their environment.
Multiple sclerosis is an autoimmune disease that affects the brain and spinal cord. Episodes can last for days, weeks or months and alternate with periods of reduced or no symptoms at all.
About the InfantRisk Center Team
Thomas Hale, Ph.D., R.Ph., is a professor of pediatrics and associate dean of research at Texas Tech University Health Sciences Center and acting executive director of the InfantRisk Center.
Hale is considered one of the foremost expert in the field of perinatal pharmacology and the use of medications by pregnant and breastfeeding mothers.
The vision of the InfantRisk Center is to create a new body of drug information concerning the safety of medications and their use during pregnancy and lactation. Additionally, the center will expand, enhance and disseminate knowledge regarding the use of medications and other environmental chemicals by pregnant and breastfeeding women worldwide.
Dr. Baker graduated from the University of Texas Southwestern and completed her residency training at Parkland Health and Hospital System in Dallas, TX. She is Board Certified by the American Board of Obstetrics and Gynecology and is a Fellow of the American College of Obstetricians and Gynecologists.
Dr. Baker has a combined private and academic OB/GYN practice with the University Physicians at Texas Tech Health Sciences Center in Amarillo. She is interested in teen pregnancy, postpartum depression, and promoting preventive medicine for the women of the Texas Panhandle, as well as Resident and Student education and serves as the Residency Director.