This is an excellent article that reviews the current knowledge about the use of various iodinated and gadoliniium-containing radio contrast agents used in CT and MRI scans.Read More
Longer lactation duration is associated with decreased prevalence of non-alcoholic fatty liver disease in women.
A longer duration of breastfeeding has been associated with multiple potential health benefits for the mother including reduction in heart disease, diabetes and certain cancers. In this study we found that breastfeeding for longer than 6 months was associated with a lower risk of non-alcoholic fatty liver disease in mid-life.Read More
This article clearly suggests you should not smoke marijuana in close proximity to your children. Pediatric allergy to secondhand marijuana smoke Seattle, WashingtonRead More
Association between exposure to macrolides and the development of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis
We've known for years that Erythromycin and perhaps azithromycin can cause pyloric stenosis in infants, but we were cautious about its use during breastfeeding, or during pregnancy in mothers. Seems from this data that erythromycin used during pregnancy or breastfeeding may not be associated with pyloric stenosis. This is probably dose-related, and perhaps time dependent, since levels in milk are low. This is good news. Thus women can potentially use macrolide antibiotics while…Read More
Breastfeeding Greater Than 6 Months Is Associated with Smaller Maternal Waist Circumference Up To One Decade After Delivery.
Breastfeeding studies continue to suggest that breastfed infants are lighter in body weight. This is probably due to changes in gut microbiome, although this is not clear yet. Good news, breastfeed your baby and give them a lighter body weight in the future.Read More
The use of 'biological' drugs that are derived from the IgG antibody, are gaining in popularity. They are used in many syndromes today and are providing major changes in lifestyle for humans. These drugs commonly work for all kinds of rheumatic or autoimmune syndromes and provide major lifestyle changes in patients. Fortunately, these IgG-type products don't transfer into breastmilk very well and therefore breastfeeding mothers can commonly use these products quite safely.Read More
Methotrexate is a rather dangerous drug and must be used really cautiously, particularly in pregnant and breastfeeding mothers. We get this call all the time in breastfeeding mothers using this drug. Fortunately we found this mother who was willing to give milk samples following high dose therapy for Placenta Accreta. This mom received 92 mg methotrexate following delivery. Interestingly, milk levels were really low. This is an antifolate drug used in many diseases, and is quite risky…Read More
First, you must know that doing research with Cannabis products is virtually impossible in the USA today. The effect of all the governmental legal restrictions, virtually stops all research. We were most fortunate to find a wonderfully supportive group of lactation consultants and cannabis using moms in Colorado, who helped us find breastfeeding mothers who were using this product while breastfeeding. Nine of these moms followed our directions, and provided milRead More
Estimation of Riluzole Levels in Human Milk and Infant Exposure During Its Use in a Patient With ALS.
This drug is a rather unusal compound that is ONLY used thus far for treating Amyotrophic lateral sclerosis. I was moved that a patient with ALS called and was continuing to breastfeed her infant, and wanted information about this drug in breastfeeding. We found that levels of Riluzole were quite low. Thanks to this heroic mom for providing milk samples during this difficult period of her life. TWHRead More
Minimal to no transfer of certolizumab pegol into breast milk: results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study.
Certolizumab is an interesting IgG molecule, that is used to treat various autoimmune disorders, ulcerative colitis, Crohn's disease. This product is rather unique, in that the transporter piece of the molecule that binds to various transporter receptor sites in humans, was clipped off. Thus certolizumab is not readily transferred via the placenta in the last trimester to the fetus. Its transfer into the milk compartment is blunted as well. This appears to beRead More