Extreme temperatures have the potential to alter the effectiveness of medications. Drugs should not be stored in areas where the temperature may exceed 86 degrees or drop below 58 degrees. Both prescription and over-the-counter medications are at risk for loss of potency and changes in chemical structure if not stored properly. Besides temperature extremes, other conditions can alter medications such as moisture, light, and time.
Topical teething products containing benzocaine have been formulated to soothe the pain of teething in infants and children. The Food and Drug Administration (FDA) has recently reported that the use of benzocaine may increase the risk of a serious medical condition called methemoglobinemia. The symptoms of this condition include blue skin, lips, and nail beds, headache, lightheadedness, tiredness, rapid heart rate, and shortness of breath. These symptoms may appear after one application. Symptoms also may appear within a few minutes to a few hours after application.
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