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Wellbutrin XL 450 while breastfeeding

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  • Wellbutrin XL 450 while breastfeeding

    Hello, I am currently taking Wellbutrin XL 300 mg while breastfeeding my 9 month old on demand. My doctor wants me to go up to 450 mg. Is this safe for my baby? I could not find any mention in the literature of a dose this high in a breastfeeding mother.

    Thank You

  • #2
    Hi AnnW,

    We have data on doses up to 300mg, which reflects reasonable levels in milk. In a 9-month-old, I would expect your higher dose to still be OK as your milk volume is decreasing. By 9 months, your baby may even be able to metabolize the drug faster than you! I would be more concerned about a young baby fully breastfeeding. I would also be more cautious if you are taking multiple medications at high doses.

    Kaytlin Krutsch, PharmD


    • #3
      Thanks so much for your response!