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Dexilant

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  • #1

    Dexilant

    I have just met with a breastfeeding mother who has Crohn's disease. I know the Remicade she gets every 8 weeks is OK for breastfeeding, but sources I have checked for Dexilant have no information about safety in breastfeeding. Do you have any recent info on this drug?
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  • #2
    Dear ksacks,

    Dexlansoprazole (Dexilant) is a new proton pump inhibitor and is the active metabolite of lansoprazole (Prevacid). Due to poor stability in stomach acid and a short half-life of one to two hours, the transfer into milk and its oral absorption is likely to be minimal in a breastfed infant. Dexlansoprazole is structurally similar to omprazole and lansoprazole. Dr. Hale rates dexlansoprazole as L2 & the time the drug is most concentrated in breastmilk is 1 to 2 hrs after taking the dose (T max). Mom may avoid the T max to decrease even further the amount of drug the infant is exposed to. Let me know if you have further questions.

    Sincerely,
    Cindy Pride. MSN, CPNP
    TTUHSC InfantRisk Center

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