Dr. Hale,
I'm not sure if you are interested, but I have a 7-month-old patient I saw in clinic that was breastfeeding BID x1 month from a Mom on pravastatin, omeprazole, metformin, & glipizide. Labs after 1 month exposure to statin were AST mildly incr'd at 68 (20-60), CK hi at 553 (37-430), LDL low at 45 (70-110), trigs hi at 278 (60-134), VLDL hi at 56 (<16).
HDL 46 (nl), glucose 88 (nl), ALT 32 (nl), TC 147 (nl).
Advised Mom to stop breastfeeding & repeated labs 1 month later.
AST still mildly incr'd at 64, LDL still low at 45, Trigs better but hi @ 184, VLDL better but hi @ 37.
CK normalized at 397.
ALT nl, TC nl @ 130, HDL nl @ 48, Glucose 94 (nl).
Only thing that was impressive was corrected CK with no longer being exposed to statin. Not really sure patient was exposed a lot, however, since only breastfeeding BID.
Interested in your comments....
Thanks,
Cheryl
I'm not sure if you are interested, but I have a 7-month-old patient I saw in clinic that was breastfeeding BID x1 month from a Mom on pravastatin, omeprazole, metformin, & glipizide. Labs after 1 month exposure to statin were AST mildly incr'd at 68 (20-60), CK hi at 553 (37-430), LDL low at 45 (70-110), trigs hi at 278 (60-134), VLDL hi at 56 (<16).
HDL 46 (nl), glucose 88 (nl), ALT 32 (nl), TC 147 (nl).
Advised Mom to stop breastfeeding & repeated labs 1 month later.
AST still mildly incr'd at 64, LDL still low at 45, Trigs better but hi @ 184, VLDL better but hi @ 37.
CK normalized at 397.
ALT nl, TC nl @ 130, HDL nl @ 48, Glucose 94 (nl).
Only thing that was impressive was corrected CK with no longer being exposed to statin. Not really sure patient was exposed a lot, however, since only breastfeeding BID.
Interested in your comments....
Thanks,
Cheryl
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