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Cymbalta and Effexor 3 months postpartum and breastfeeding

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  • Cymbalta and Effexor 3 months postpartum and breastfeeding

    Can you please direct me to literature/research on Cymbalta and Effexor in breastfeeding women, specifically that address the infant dose received and transfer into breastmilk?

  • #2
    Cymbalta Papers:

    Lobo ED, Loghin C, Knadler MP et al. Pharmacokinetics of duloxetine in breast milk and plasma of healthy postpartum women. Clin Pharmacokinet. 2008;47:103-109.

    Briggs GG, Ambrose PJ, Ilett KF, Hackett LP, Nageotte MP, Padilla G. Use of duloxetine in pregnancy and lactation. Ann Pharmacother. Nov 2009;43(11):1898-1902.

    Boyce PM, Hackett LP, Ilett KF. Duloxetine transfer across the placenta duringpregnancy and into milk during lactation. Arch Womens Ment Health 2011;14(2):169-72.

    Effexor Papers:

    Ilett KF, Kristensen JH, Hackett LP, Paech M, Kohan R, Rampono J. Distribution of venlafaxine and its O-desmethyl metabolite in human milk and their effects in breastfed infants. Br J Clin Pharmacol 2002; 53(1):17-22.

    Newport DJ, Ritchie JC, Knight BT, Glover BA, Zach EB, Stowe ZN. Venlafaxine in human breast milk and nursing infant plasma: determination of exposure. J Clin Psychiatry. Sep 2009;70(9):1304-1310.

    Tran MM, Fancourt N, Ging JM et al. Failure to thrive potentially secondary to maternal venlafaxine use. Australas psychiatry 2016;24(1):98-9.

    Koren G, Moretti, Kapur B. Can Venlafaxine in Breast Milk Attenuate the Norepinephrine and Serotonin Reuptake Neonatal Withdrawal Syndrome? JOGC 2006 April; 28(4):299-302.