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Breastfeeding after chemo

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  • Breastfeeding after chemo

    I was diagnosed with colon cancer 2 months ago, am 5 weeks out of surgery and start chemo with 5 FU and Oxilplatin in 2 weeks. I will do treatments every 2 weeks for 6 months (12 treatments). My baby will be 8 months on Sept. 5th, I start treatment on the 10th. How long do I need to wait to breastfeed after treatment. (Will there be any time between treatments to breastfeed?)

  • #2
    My4girls, thanks for posting,

    5 FU is rated an L4-limited data-possibly hazardous. If used orally, or intravenously in significant doses, a suitable waiting period should be used to avoid exposure of the infant. Because it has only a 12 minute half-life, a waiting period of at least 24 hours or more would probably reduce any risk from this agent.

    Oxaliplatin is rated an L5-no data-hazardous. Oxaliplatin is a platinum compound with similar kinetics to cisplatin. Oxaliplatin is extensively bound in peripheral tissues, which accounts for its extraordinarily long terminal elimination half-life (391 hours). While breast milk levels are unavailable, but are probably low, breastfeeding is not advisable for weeks and should probably be discontinued for this infant, unless milk platinum levels could be measured. Two options are suggested. One, breast milk should be tested for platinum levels and not used as long as they are measurable. Two, without measuring platinum levels, breastfeeding should be permanently interrupted for this infant.

    I hope this helps. If you have any other questions please call the InfantRisk Center at 806-352-2519. Thanks,

    Sandra Lovato R.N.
    InfantRisk Center

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    • #3
      Originally posted by Sandra Lovato View Post
      My4girls, thanks for posting,

      5 FU is rated an L4-limited data-possibly hazardous. If used orally, or intravenously in significant doses, a suitable waiting period should be used to avoid exposure of the infant. Because it has only a 12 minute half-life, a waiting period of at least 24 hours or more would probably reduce any risk from this agent.

      Oxaliplatin is rated an L5-no data-hazardous. Oxaliplatin is a platinum compound with similar kinetics to cisplatin. Oxaliplatin is extensively bound in peripheral tissues, which accounts for its extraordinarily long terminal elimination half-life (391 hours). While breast milk levels are unavailable, but are probably low, breastfeeding is not advisable for weeks and should probably be discontinued for this infant, unless milk platinum levels could be measured. Two options are suggested. One, breast milk should be tested for platinum levels and not used as long as they are measurable. Two, without measuring platinum levels, breastfeeding should be permanently interrupted for this infant.

      I hope this helps. If you have any other questions please call the InfantRisk Center at 806-352-2519. Thanks,

      Sandra Lovato R.N.
      InfantRisk Center
      I'm newly register on that forum and looking for the advice about colon cancer for my wife. I'm really thankful for that information I hope it will work

      Comment


      • #4
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