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Oxycodone prolonged intake and breastfeeding

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  • Oxycodone prolonged intake and breastfeeding

    I've taken oxycodone-acetaminophen 5-325 (plus 400mg of iboorufen) every 4-6h from November 12th to December 8th (every 4h in the last days)
    I was avoiding breastfeeding and stopped it one week after I started taking this medication, but my daughter still asks for it and didn't meant to wean her abruptly
    How long should I wait to restart breastfeeding after stopping oxycodone? I am still taking iboorufen but her doctor said it's ok.

    Thank you!

  • #2

    If you are stopping the medication you should be ok to nurse after a few hours. The half-life of oxycodone is 2-4 hours. If you want it to be completely out wait 5-6 half lives which would be anywhere from 12-24 hours. We think taking oxycodone is probably ok for short term use. We recommend that you do not exceed 30mg in 24 hours while nursing a younger infant and no more than 40mg in older infants. We recommend taking the medication right after nursing where you have a break before nursing again to avoid the peak time. Monitor your infant for sedation, slowed breathing rate, pallor, difficulty feeding, constipation and apnea.

    Sandra Lovato R.N.
    InfantRisk Center