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I am specifically looking into its application for the treatment of Androgenetic Alopecia. As I understand, this is an off-label use, and information regarding its safety profile during lactation is currently very limited.
I have located the following study which seems highly relevant, but I do not have access to the full text:
Given the long half-life of dutasteride when taken orally, I am concerned about the potential systemic absorption and its impact on the breastfed infant when applied topically.
Do you have any additional records, pharmacokinetic data on systemic absorption from scalp application, or expert consensus regarding the Lactation Risk Category for the topical form of this substance?
Thank you very much for your time and for the invaluable service you provide.
I have located the following study which seems highly relevant, but I do not have access to the full text:
- Topical dutasteride for the treatment of androgenetic alopecia in a breastfeeding woman: A case report and literature review ([url]https://onlinelibrary.wiley.com/doi/10.1111/ijd.17940[/url]).
Given the long half-life of dutasteride when taken orally, I am concerned about the potential systemic absorption and its impact on the breastfed infant when applied topically.
Do you have any additional records, pharmacokinetic data on systemic absorption from scalp application, or expert consensus regarding the Lactation Risk Category for the topical form of this substance?
Thank you very much for your time and for the invaluable service you provide.