A new and novel treatment for POSTPARTUM DEPRESSION has just been introduced and is indicated for severe refractory PPD. Derived from the natural steroid hormone, allopregnanolone, this novel steroid acts directly in the brain to reduce depression. Its only problem is that it requies a 60 hour IV infusion of drug in a clinical environment. Studies show it is highly effective. Again, its indicated for SEVERE refractory PPD.