Levofloxacin?

[M&J’sMommy]

My doctor started me on Amoxicillin for a ear infection in right ear. It didn’t work and now I have a ear infection in left ear. According to Dr. infection looks pretty bad in both so she prescribed Levofloxacin 500mg once a day for 7 days. I have a 3 month old who exclusively breastfeeds, can I continue to breastfeed her without worry?

[admin]

MJ Mommy:

Levofloxacillin is not ideal as the dose ranges up to 17% of the maternal dose, but we thing the dose the infant gets is really much lower. I'd suggest you wait about 4-5 hours AFTER the dose to to breastfeed the infant to reduce the exposure to the infant.

Tom Hale Ph.D.

[M&J’sMommy]

Okay, is their any alarming side affects I should look out for with my daughter?

[admin]

MJ:

These are reported in the package insert. Not sure you'd ever notice these in a breastfed infant. I'd suggest pain, or gastric distress such as vomiting, diarrhea.

Tom Hale

Pediatrics: Musculoskeletal disorders (arthralgia, arthritis, tendinopathy, and gait abnormality) seen in more levofloxacin-treated patients than in comparator. Shown to cause arthropathy and osteochondrosis in juvenile animals (5.12 ([url]https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8962eb50-3366-1eec-44f9-170e686d2d66#ID_cb026fd5-4e02-4f1a-bfe0-b9888267d3d4[/url]), 8.4 ([url]https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8962eb50-3366-1eec-44f9-170e686d2d66#ID_edb66b30-5d88-4bd7-af8b-8b3cfeeac0aa[/url]), 13.2 ([url]https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8962eb50-3366-1eec-44f9-170e686d2d66#ID_c210b7e4-317a-45db-8c83-a235097cbec3[/url])). Safety in pediatric patients treated for more than 14 days has not been studied.