Natalizumab is a monoclonal antibody that is only used in humans with multiple sclerosis.  It is somewhat toxic, and we were interested to see if this large monoclonal antibody transfers into human milk.  Levels in milk appear low,  but I made a mistake in the timing of the study, and should have drawn milk levels several mosts longer.  I need to redo this study and go out to about 120 days.   However, at this point, I still think milk levels are subclinical.   TWH

 

This is one of the InfantRisk Centers studies.  We found that levels of linezolid in human milk are really low.  Good news if a mom needs this drug.   TWH

 

Title: Transfer of linezolid into breast milk.

Authors: Rowe HE, Felkins K, Cooper SD, Hale TW.

All of us who work in pediatrics know that adequate thyroid function in a newborn is absolutely critical for the infants development.  Nothing is worse than hypothyroidism in a newborn infant.  While the infant needs low to modest levels of potassium iodine to make all the thyroxin it needs,  TOO MUCH iodine basically shuts the infant thyroid down.  Remember,  there is a pump in the human breast that collects all iodine molecules that pass the mothers breast and transfers that iodine molecule into the milk.  This was nature's way to make sure the baby could make

This interesting article confirms what we've suggested for some time, that Zika virus is transferred into human milk. However,  should a mom with Zika stop breastfeeding,  apparently not,  no abnormalities were found in these infants.  TWH

 

Many of us have thought for some time that to avoid cows milk allergy in infants, we could avoid this problem by using the hydrolyzed infant formulas rather than the cows milk formulas.  Seems the evidence doesn't support this theory.  TWH

 

This study further confirms what we've thought for some time,  that the Warfarin anticoagulant was safe to use in breastfeeding mothers.  TWH

 

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