Apparent Pediatric allergy to secondhand marijuana smoke.

Pediatric allergy to secondhand marijuana smoke

A six year old boy with severe asthma, which was not responding to treatment, was found to be allergic to secondhand marijuana smoke. He had daily symptoms of cough, shortness of breath and wheezing. It was discovered that some family members had started smoking marijuana in the house, although never in the same room as the boy.

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Safety of Contrast Material Use During Pregnancy and Lactation

This is an excellent article that reviews the current knowledge about the use of various iodinated and gadoliniium-containing radio contrast agents used in CT and MRI scans. While the iodinated compounds are probably safe to use in breastfeeding mothers,  there is some concern over the "repeated" use of the metal-containing gadoliniium products used for MRI scans.  Excellent review of this subject.  TWH

SUMMARY from this article:

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Longer lactation duration is associated with decreased prevalence of non-alcoholic fatty liver disease in women.

A longer duration of breastfeeding has been associated with multiple potential health benefits for the mother including reduction in heart disease, diabetes and certain cancers. In this study we found that breastfeeding for longer than 6 months was associated with a lower risk of non-alcoholic fatty liver disease in mid-life.

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Pediatric allergy to secondhand marijuana smoke

This article clearly suggests your should not breastfeed in close proximity to your children.

 

Pediatric allergy to secondhand marijuana smoke

Seattle, Washington

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Association between exposure to macrolides and the development of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis

We've known for years that Erythromycin and perhaps azithromycin can cause pyloric stenosis in infants,  but we were cautious about its use during breastfeeding, or during pregnancy in mothers.  Seems from this data that erythromycin used during pregnancy or breastfeeding may not be associated with pyloric stenosis.  This is probably dose-related, and perhaps time dependent,  since levels in milk are low. This is good news.  Thus women can potentially use macrolide antibiotics while breastfeeding.  I still think they are not the best choice early postpartum in breastfeeding mothers and physicians should choose an alternate, just in case the first few months postpartum. 

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Breastfeeding Greater Than 6 Months Is Associated with Smaller Maternal Waist Circumference Up To One Decade After Delivery.

Breastfeeding studies continue to suggest that breastfed infants are lighter in body weight.  This is probably due to changes in gut microbiome, although this is not clear yet.  Good news,  breastfeed your baby and give them a lighter body weight in the future. 

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Anti-TNF Exposure during Pregnancy in Crohn's Disease Patients.

The use of 'biological' drugs that are derived from the IgG antibody, are gaining in popularity.  They are used in many syndromes today and are providing major changes in lifestyle for humans.  These drugs commonly work for all kinds of rheumatic or autoimmune syndromes and provide major lifestyle changes in patients.  Fortunately,  these IgG-type products don't transfer into breastmilk very well and therefore breastfeeding mothers can commonly use these products quite safely. 

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High-Dose Methotrexate Treatment in a Breastfeeding Mother with Placenta Accreta: A Case Report.

Methotrexate is a rather dangerous drug and must be used really cautiously, particularly in pregnant and breastfeeding mothers.  We get this call all the time in breastfeeding mothers using this drug.  Fortunately we found  this mother who was willing to give milk samples following high dose therapy for Placenta Accreta.   This mom received 92 mg methotrexate following delivery.  Interestingly,  milk levels were really low.  This is an antifolate drug used in many diseases,  and is quite risky around pregnant women and previously I thought in breastfeeding mothers.  This data suggests that milk levels of methotrexate, even following this high dose,  are quite low (RID= 0.11%).  This was one of those questions I always hated to answer,  because we had NO data on its transmission into human milk, and its relatively dangerous.   Seems its levels in milk are very low.  We still need to be cautious,  but I can rest a bit easier now.   TWH

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Transfer of Inhaled Cannabis Into Human Breast Milk.

First, you must know that doing research with Cannabis products is virtually impossible in the USA today.  The effect of all the governmental legal restrictions, virtually stops all research.  We were most fortunate to find a wonderfully supportive group of lactation consultants and cannabis using moms in Colorado,  who helped us find breastfeeding mothers who were using this product while breastfeeding.  Nine of these moms followed our directions, and provided milk samples.  This is one of the first really accurate assessments of THC transfer into human milk.  W

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Estimation of Riluzole Levels in Human Milk and Infant Exposure During Its Use in a Patient With ALS.

This drug is a rather unusal compound that is ONLY used thus far for treating  Amyotrophic lateral sclerosis.  I was moved that a patient with ALS called and was continuing to breastfeed her infant, and wanted information about this drug in breastfeeding.  We found that levels of Riluzole were quite low.  Thanks to this heroic mom for providing milk samples during this difficult period of her life.  TWH

 

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