A longer duration of breastfeeding has been associated with multiple potential health benefits for the mother including reduction in heart disease, diabetes and certain cancers. In this study we found that breastfeeding for longer than 6 months was associated with a lower risk of non-alcoholic fatty liver disease in mid-life.

This article clearly suggests your should not breastfeed in close proximity to your children.

 

Pediatric allergy to secondhand marijuana smoke

Seattle, Washington

We've known for years that Erythromycin and perhaps azithromycin can cause pyloric stenosis in infants,  but we were cautious about its use during breastfeeding, or during pregnancy in mothers.  Seems from this data that erythromycin used during pregnancy or breastfeeding may not be associated with pyloric stenosis.  This is probably dose-related, and perhaps time dependent,  since levels in milk are low. This is good news.  Thus women can potentially use macrolide antibiotics while breastfeeding.  I still think they are not the best choice early postpartum in breastfeeding mothers and physicians should choose an alternate, just in case the first few months postpartum. 

Breastfeeding studies continue to suggest that breastfed infants are lighter in body weight.  This is probably due to changes in gut microbiome, although this is not clear yet.  Good news,  breastfeed your baby and give them a lighter body weight in the future. 

The use of 'biological' drugs that are derived from the IgG antibody, are gaining in popularity.  They are used in many syndromes today and are providing major changes in lifestyle for humans.  These drugs commonly work for all kinds of rheumatic or autoimmune syndromes and provide major lifestyle changes in patients.  Fortunately,  these IgG-type products don't transfer into breastmilk very well and therefore breastfeeding mothers can commonly use these products quite safely. 

Methotrexate is a rather dangerous drug and must be used really cautiously, particularly in pregnant and breastfeeding mothers.  We get this call all the time in breastfeeding mothers using this drug.  Fortunately we found  this mother who was willing to give milk samples following high dose therapy for Placenta Accreta.   This mom received 92 mg methotrexate following delivery.  Interestingly,  milk levels were really low.  This is an antifolate drug used in many diseases,  and is quite risky around pregnant women and previously I thought in breastfeeding mothers.  This data suggests that milk levels of methotrexate, even following this high dose,  are quite low (RID= 0.11%).  This was one of those questions I always hated to answer,  because we had NO data on its transmission into human milk, and its relatively dangerous.   Seems its levels in milk are very low.  We still need to be cautious,  but I can rest a bit easier now.   TWH

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