Hi Dr Hale
I have a question regarding two "generic" brands of domperidone 10mg that are manufactured in India and sold through the internet company inhousepharmacy.biz
Domperon 10mg by Cadilla - this is actually sublingual
Vomistop 10mg by Cipla
I am hoping to sit the exam to become an IBCLC this year and in my studies I found that different brands may not be bioequivalent due to their excipients, even though I always thought generic drugs were exactly the same (that's what the pharmacy tells me when I buy my medications!). I'm a little concerned because many mothers in the US and possibly my own country, Australia, have turned to these brands as they are cheaper than Jannsen's Motilium. I have emailed the companies to find out what their excipients are and if it is bioequivalent to Motilium but haven't heard back from them *surprise surprise*
Do you have any way to find out whether mothers may be taking something that is not effective, or as effective as Motilium?
Would the sublingual one, Domperon, have a different effect if mothers are swallowing whole with a glass of water, as some are?
Finally, I myself had to take Domperidone for both my babies due to my own insufficient glandular tissue (or hypoplastic breasts). I had differing advice from pharmacists as to whether I had to follow the domperidone instructions on taking 30 min before meals, or if it didn't matter if I wasn't taking it for the gastrointestinal effect. What is your recommendation?
I would really appreciate your advice on this.
Thankyou for all your hard work in the field of breastfeeding medicine!
Naomi
I have a question regarding two "generic" brands of domperidone 10mg that are manufactured in India and sold through the internet company inhousepharmacy.biz
Domperon 10mg by Cadilla - this is actually sublingual
Vomistop 10mg by Cipla
I am hoping to sit the exam to become an IBCLC this year and in my studies I found that different brands may not be bioequivalent due to their excipients, even though I always thought generic drugs were exactly the same (that's what the pharmacy tells me when I buy my medications!). I'm a little concerned because many mothers in the US and possibly my own country, Australia, have turned to these brands as they are cheaper than Jannsen's Motilium. I have emailed the companies to find out what their excipients are and if it is bioequivalent to Motilium but haven't heard back from them *surprise surprise*
Do you have any way to find out whether mothers may be taking something that is not effective, or as effective as Motilium?
Would the sublingual one, Domperon, have a different effect if mothers are swallowing whole with a glass of water, as some are?
Finally, I myself had to take Domperidone for both my babies due to my own insufficient glandular tissue (or hypoplastic breasts). I had differing advice from pharmacists as to whether I had to follow the domperidone instructions on taking 30 min before meals, or if it didn't matter if I wasn't taking it for the gastrointestinal effect. What is your recommendation?
I would really appreciate your advice on this.
Thankyou for all your hard work in the field of breastfeeding medicine!
Naomi
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