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  • Progesterone Injections

    Was suggested to take progesterone in oil injections at 100mg/ml. Is this safe for baby? Has it been studied? Thanks.

  • #2
    Honeybear:

    If during pregnancy it is commonly used to prevent prematurity. See below.

    Tom Hale Ph.D.

    Int J Womens Health. ([url]https://www.ncbi.nlm.nih.gov/pubmed/28553146#[/url]) 2017 May 17;9:331-345. doi: 10.2147/IJWH.S100817. eCollection 2017.


    Recurrent pregnancy loss: current perspectives.


    Abstract


    Recurrent pregnancy loss is an important reproductive health issue, affecting 2%-5% of couples. Common established causes include uterine anomalies, antiphospholipid syndrome, hormonal and metabolic disorders, and cytogenetic abnormalities. Other etiologies have been proposed but are still considered controversial, such as chronic endometritis, inherited thrombophilias, luteal phase deficiency, and high sperm DNA fragmentation levels. Over the years, evidence-based treatments such as surgical correction of uterine anomalies or aspirin and heparin for antiphospholipid syndrome have improved the outcomes for couples with recurrent pregnancy loss. However, almost half of the cases remain unexplained and are empirically treated using progesterone supplementation, anticoagulation, and/or immunomodulatory treatments. Regardless of the cause, the long-term prognosis of couples with recurrent pregnancy loss is good, and most eventually achieve a healthy live birth. However, multiple pregnancy losses can have a significant psychological toll on affected couples, and many efforts are being made to improve treatments and decrease the time needed to achieve a successful pregnancy. This article reviews the established and controversial etiologies, and the recommended therapeutic strategies, with a special focus on unexplained recurrent pregnancy losses and the empiric treatments used nowadays. It also discusses the current role of preimplantation genetic testing in the management of recurrent pregnancy loss. KEYWORDS:

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    • #3
      No, during breastfeeding.

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      • #4
        Honeybear:

        It could prove problematic during breastfeeding, particularly early postnatal breastfeeding, when the breast could still be very sensitive to high levels of progesterone.

        After the first week or so, it is unlikely to cause problems 'for breastfeeding', but if the levels are high enough, it could cause feminization of the male infant and perhaps some for the female infant.

        I'd be cautious using injectable progesterone during breastfeeding for an extended length of time.

        Tom Hale Ph.D.

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