I've been on ABVD chemotherapy for Hodgkin's lymphoma for the past 3 months, hoping to start breastfeeding in between treatments, understanding I have to wait 10 days for these drugs to clear my system. But I've been having a lot of trouble with my milk supply. I'm wondering if my chemo drugs are affecting my ability to produce milk? Would ABVD chemotherapy kill off lactocytes?
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Chemotherapeutic agents targeting lactocytes?
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Anneke:
Galactagogues like domperidone are great IF you have low prolactin levels. I'd have your doctor draw a blood sample 2 hours after breastfeeding, and measure prolactin levels. If they are < 50 ng/mL, then domperidone would work great.
As domperidone may alter your heart beat, have your doctor do an EKG first and keep the dose 30-60 mg per day. (Evaluate for Prolonged QT interval)
Withhold periods for these drugs is :
Doxorubicin : 7-10 minimum
Bleomycin : 24 hours minimum
Vinblastine: 10 days minimum
Dacarbazine : 48 hours minimum
Tom Hale Ph.D.
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