Gastrocrom

[PepperPOTS]

I have recently been diagnosed with Mast Cell Activation Syndrome (MCAS) and am currently taking two ampules of Gastrocrom BID and am working up to a dose of two ampules QID. When my symptoms are better managed, I am planning to adopt a newborn and would ideally like to adoptive breastfeed. However, as far as I know, there has been no research done on Gastrocrom and breastfeeding and I am wondering whether it might be contraindicated. Any information would be greatly appreciated!

Also, I take 20 mg loratadine BID and 40 mg famotidine BID. From what I have read, a single dose of these antihistamines is considered safe while breastfeeding. Are the amounts I'm taking safe?

Thank you, in advance, for your help!

[cpride]

Dear PepperPOTS,

Cromolyn Sodium (Gastrocrom) supresses mast cell degranulation. We do not have data on breastmilk levels. We do know that only one percent of your dose is absorbed orally; therefore, unlikely to pass into breastmilk in clinically relevant amounts. Cromolyn is an extremely safe drug and is probably compatible with breastfeeding. Loratadine has low levels in breastmilk. You are on a higher dose than is typically given but is likely compatible with breastfeeding. Observe your infant for sedation. Famotidine is a typical histamine-2 receptor antagonist that reduces stomach acid secretion. Levels in milk are low. Famotidine is probably safe to use during breastfeeding. If you have further questions, please call us at the InfantRisk Center, 806-352-2519. We are open Monday through Friday, 8 to 5, CST.

Sincerely,
Cindy Pride, MSN, CPNP
TTUHSC InfantRisk Center