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ACTH stimulation test and IV Cosyntropin

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  • #1

    ACTH stimulation test and IV Cosyntropin

    Hello,
    I am working with a mom who is going to undergo an ACTH stimulation test which includes IV injection of Cosyntropin (synthetic ACTH). How soon after completion of the study would she be able to breast feed? Her infant is 6 months old. Thank you.
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  • #2
    Dear Lactationhelper,

    ACTH is secreted by the anterior pituitary in the brain and stimulates the adrenal cortex to produce and secrete adrenocortical hormones (cortisol, hydrocortisone). As a peptide product, ACTH is easily destroyed in the infants' GI tract. None would be expected to be absorbed by the infant. Brief exposures are probably not contraindicated. The half-life is 15 minutes. If mom is worried, she can pump and discard once at two hours then continue breastfeeding but not necessary.

    Sincerely,
    Cindy Pride, MSN, CPNP
    TTUHSC InfantRisk Center

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